At least 37 Palestinians have been killed and 1,300 wounded by Israeli troops in clashes on the Gaza border according to Palestinian officials.
The violence comes on the day the US opens its embassy in Jerusalem - a move which has angered Palestinians.
US President Trump did not attend the ceremony but sent senior advisors - his daughter Ivanka and her husband Jared Kushner.
Kate Fisher reports from Washington.
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President Trump, in a video message, insisted that the United States can still play a role brokering peace negotiations between the Israelis and the Palestinians.
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