The Caribbean island could see winds of 175 miles per hour, and over 100 centimetres of rain.
Melissa is a category five hurricane, and the storm has already caused several deaths in Jamaica, Haiti and the Dominican Republic.
Jamaican Prime Minister Andrew Holness says people must prepare for the worst.
IN: 'We have....
OUT: ...island.'
DUR: 14 seconds
http://www.fsnradionews.com/feeds/1028melissa-holness1.mp3